Web6 apr 2016 · Veratri Nigri Rhizoma et Radix (Veratrum nigrum L.) and Its Constituent Jervine Prevent Adipogenesis via Activation of the LKB1-AMPKα-ACC Axis In Vivo and In Vitro. ... WebJervine, CAS: 469-59-0, is a naturally occuring steroidal alkaloid that can inhibit the sonic hedgehog pathway. Cited in 1 publications
NCATS Inxight Drugs — JERVINE
Web6 apr 2016 · Jervine (PubChem CID: 10098) was purchased from Sigma Chemical Co. (St. Louis, MO, USA). 2.3. HPLC Analysis The chromatographic system consisted of Jasco HPLC-LC-2000 Plus (Tokyo, Japan) equipped with a Jasco MD-2024 Plus Photodiode Array Detector, using the Mightysil RP-18 (L) GP column (5 μ m, 4.6 × 150 mm, Kanto … WebCell-permeable. Structurally similar to cyclopamine (Cat. No. 1578). Inhibits the sonic hedgehog (shh) pathway by interacting with smoothened. Jervine can be used to induce … biochemical imbalances can affect behaviour
mzCloud – Jervine
WebLa jervine est un alcaloïde stéroïde issu de plantes du genre Veratrum (vératres). Semblable à la cyclopamine , il s'agit d'une substance tératogène qui provoque des malformations congénitales graves chez les fœtus lorsqu'elle est consommée par des animaux lors de certaines phases de la gestation , pouvant provoquer des cas de … WebJervine is a potent teratogenic agent. It can induce apoptosis in leukemia cells and MUTZ-1 cells. Jervine is an inhibitor of Hedgehog signaling. It exhibits anti-cancer effects on … WebJervine ((3β, 23β)-17,23-Epoxy-3-hydroxyveratraman-11-one ); ≥ 98% HPLC, powder; Jervine is a sonic hedgehog (Shh) pathway inhibitor; PL PL. Applications Products Services Support. J4145; All Photos (1) ... Identyfikator substancji w PubChem: 24896194. NACRES: NA.77. Recommended Products. biochemical imbalance in the brain