Web1 May 2016 · A blister is defined as a saccular skin vesicle filled with serous fluid, which separates the epidermis and/or dermis, and which may be linked to shearing forces … Web22 Feb 2024 · A blister can develop if the skin is rubbed for a long period or if there's intense rubbing over shorter periods. Friction blisters often occur on the feet and hands, which …
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